So you have been away on vacation and as soon as you get home you want to get those e-mails you have been missing while you were away. Well, before you do, remember you have been away for 2 weeks. At the present rate of 300+ viruses a month, you may have 150 new viruses since you left for your vacation.
This means there may be new viruses from all your fiends sitting in your e-mail or on a website waiting for you to visit. These virus people rely on this type of behavior.
SO .... UPDATE your virus scanner FIRST before you go anywhere or get any new e-mails!